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Contents
1.
Forms of Iodine ................................................................................................................... 3
2.
How much Iodine do I need to take? .................................................................................. 3
3.
Supporting Nutrients for taking Iodine ............................................................................... 4
4.
Why do we take these supplements as part of the protocol? ........................................... 5
5.
When should I take my supplements? Do I need to space them apart? ........................... 6
6.
Does iodine destroy good bacteria? ................................................................................... 6
7.
How long should I take Iodine? .......................................................................................... 6
8.
Where can I buy non-liquid Lugol’s products? ................................................................... 7
9.
What is the Salt Loading Protocol? ..................................................................................... 7
10.
What are the sources of Bromide? ..................................................................................... 7
11.
Validity of the Iodine Patch Test ......................................................................................... 8
12.
My ferritin dropped while on Iodine. ................................................................................. 8
13.
I am gaining weight since starting Iodine. .......................................................................... 8
14.
Iodine Supplementing & Mercury Filings ........................................................................... 8
15.
I have Hashimotos. Can I take Iodine? ............................................................................... 8
16.
Why does iodine work for Hashimotos? ........................................................................... 10
17.
My TSH went up on Iodine................................................................................................ 11
18.
I have adrenal fatigue. Can I take Iodine?........................................................................ 11
19.
I have breast cancer and would like to learn more about using Iodine. .......................... 11
20.
Bromide Toxicity and Iodine Loading Test. ....................................................................... 11
21.
Ordering a 24 hour Iodine Loading Test with Bromide Levels. ......................................... 12
22.
Recommended Reading. ................................................................................................... 13
23.
Detoxification .................................................................................................................... 14
24.
Importance of Healthy Gut Flora ...................................................................................... 19
25.
Detox Strategies ................................................................................................................ 19
26.
Final thoughts as it relates to Iodine Supplementing Detox….. ........................................ 21
27.
INDEX ................................................................................................................................ 22
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**NOTE: This document is for educational purposes only. It is not meant to treat or diagnose any medical
condition. Please seek the help of a qualified medical practitioner for any medical issues.
1.
Forms of Iodine
a.
Nascent (aka Magnascent, Detoxified or Atomidine) – Based on Edgar Cayce’s
“energized” iodine. The iodine is reduced to a 1% concentration in 100% ethyl alcohol
and electro-magnetically transmuted (while being suspended in a wet bath containing a
mild acid solution) into the Atomic state. 1 drop = 150 mcg or .150 mg of Iodine. This
form will not saturate body tissues and has not been proven to detox halides such as
bromide, fluoride, chloride, and mercury, as other forms have.
b.
Lugol’s Formula – This is an iodine formula of Iodine and Potassium Iodide (5% Iodine /
10% Potassium Iodide in water). Two drops of this 5% solution contains 5 mg of iodine
and 7.5 mg of iodide – or commonly called 12.5 mg in tablet forms. Lugol’s is supplied
in milligram (mg) amounts vs other forms that are in micro gram amounts. This is the
preferred form of iodine supplementation as the body needs both forms of this nutrient.
The thyroid needs iodide and the breasts and prostate need iodine. Many other
tissues in the body can concentrate either form. These include glands like the salivary,
liver, spleen, kidneys and intestines.
c.
KELP –
While kelp does contain iodine it is not as high as you might be led to believe.
Kelp is a plant that is designed to clean toxins from the sea. Our oceans are getting
more and more contaminated with dumping from pharmaceutical and industrial
processing companies along with the Fukushima disaster which dumped large amounts
of toxic radioactive material into the ocean. Kelp has been tested and found to be high
in arsenic. For those concerned with health this is not a viable option.
It is recommended that the user consume Lugol’s formula. This is because it offers the
best solution for tissue saturation. When you consider the usage of iodine for thyroid
hormone creation plus halide protection, the recommended 150 mcg amount by the
RDA falls pathetically short. The body is reported to store 1,500 mgs of iodine in total.
The thyroid gland stores 50 mgs. Twenty percent of the total iodine is held in the skin.
Approximately 32% of iodine is stored in the muscles. This is why it is believed that
there are strong ties to fibromyalgia pain when the patient is iodine deficient.
**NOT GOOD FORMS**
2.
How much Iodine do I need to take?
There are no set amounts that can be given as a blanket recommendation. Everyone needs
different amounts based on their body’s ability to utilize the nutrients as well as the level of
toxic halide exposure they have each day. If you are dealing with a severe health condition then
your dosages will need to be higher than those trying to maintain good health.
a.
Maintenance – It was once believed that a good maintenance dose is 25 mgs per day.
But with more information being gained about the exposures to halides bombarding our
systems (bromides, fluorides, chlorine) as well as mercury, etc., maintenance of health
may require higher doses of iodine. The iodine doctors are now beginning to believe
that 50 mgs may be the minimum required dose. Many iodine group members are
finding that dosages of 100 mgs cause them to feel the best. While this is anecdotal
information it is interesting to note.
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b.
Pregnancy / Lactation – Iodine is important for both the mother and the baby. Children
who do not receive enough iodine in the womb while developing can develop cretinism.
Because iodine has the ability to push toxins out of the body (bromide, fluoride,
mercury, and lead) it is not desirable to push this to the blood stream so that it crosses
the placenta to the baby. During the 2007 Iodine Conference, the doctors discussed this
issue. Their final conclusion was to recommend that iodine be supplemented at 12.5
mgs per day if no prior supplementing / detoxing has been done before getting
pregnant. This applies to starting during lactation as well. One thing to note is that the
iodine will change the taste of the milk so if the baby refuses the breast, back the
dosage down and add slowly so that they can get used to the taste. If there is concern
over bromide toxicity then a blood test may be performed to test for circulating levels.
c.
Cancer – Cancer is a result of mutated cells. Iodine is absolutely critical for something
called the P53 gene which is known as the “keeper of the genetic code”. Without iodine
and selenium it will not function correctly to eliminate abnormal cells from the body
such as cancer. Cancer patients have taken anywhere from 50 – 300 mgs / day
successfully. Here is a good article on how P53 works with the mdm2 in cancer
http://www.sciencedaily.com/releases/2007/10/071015215101.htm If you would like
additional information on the P53 and Iodine see the Minerals for the Genetic Code
book.
d.
Children – These are the levels that I gave my children at the various ages. This is not
meant to be a recommendation but a guideline for what was safe for my children and
others I have been in contact with. General guidelines suggest .08 mg x the weight of
the child but is dependent on the health condition.
i.
Up to 3 years – 3 drops of Detoxified Iodine (www.iodinesource.com) per day or
take 1 drop of 5% Lugol’s solution in water and then take ½ of the water and
give it to the child. This results in 3.125 mgs / dose.
ii.
3yrs to 5 yrs – 6.25 mgs of Iodoral or 1 drop 5% Lugols Solution(6.25 mgs)
iii.
5 yrs to 9 yrs – 12.5 mgs of Iodoral or 2 drops 5% Lugols Solution (12.5 mgs)
iv.
9 yrs to 16 yrs – 25 mgs of Iodoral or 4 drops 5% Lugols Solution (25 mgs)
v.
16 yrs and up – will depend on health issues, weight, etc and cannot be given in
generalities. By this point their body is adult size. Dosages range from 12.5 mgs
to 300 mgs.
3.
Supporting Nutrients for taking Iodine
These nutrients are required to support the body while supplementing with iodine.
Adult Supporting Nutrients
a.
Vitamin C – 2,000 – 5,000 mgs / day
b.
Selenium – 200 – 400 mcg / day
c.
Unrefined salt (Celtic) – ½ tsp / day – supports adrenals, binds to bromide and assists in
removal, supports symporters (sodium iodine symporters or NIS)
d.
Magnesium – 200 - 400 mgs / day
e.
Optional – ATP CoFactors (B2/B3 combo) -1 tablet 2x / day (Why this is optional
discussed later on in this document).
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Children Supporting Nutrients
(based on my children)
f.
Vitamin C – 1,000 mgs per day. We used a children’s chewable.
g.
Magnesium – we did not supplement specifically with it but used a good professional
grade multivitamin.
h.
Selenium – 100 mcg – 3x / week. I purchased capsules and emptied them into
applesauce.
i.
Unrefined Salt – We use Celtic and Redmond Real Salt. I placed course ground salt and
let my children eat it out of the cups and put on their food at will.
4.
Why do we take these supplements as part of the protocol?
a.
Vitamin C – This nutrient is high in antioxidants and works to buffer the oxidation
caused by the detoxing of halides from the cells. Vitamin C is also needed by the
symporters and helps to support them in their healing process which allows iodine to
more readily enter the cells. See https://optimox.com/pics/Iodine/IOD-11/IOD_11.htm
Evidence that the administration of Vitamin C improves a defective cellular transport
mechanism for iodine: A Case Report for additional information.
b.
Selenium – Selenium is used by the thyroid in the hormone creation process. There is a
selenium containing enzyme glutathione peroxidase which functions to keep the
hydrogen peroxide reduced to H2O after it converts iodide to iodine. This keeps H2O2
from damaging the tissues. When selenium is deficient this process of defense is
impaired. This can cause oxidative damage to TPO which could be the start of
autoimmune thyroiditis.
Selenium is also contained in iodothyronine deiodinase. This is an enzyme that is
responsible for the conversion of T4 to T3 (inactive to active hormone). A deficiency in
selenium would decrease this conversion activity.
Selenium is also needed for glutathione production in the liver which assist with
detoxification of the body.
c.
Magnesium – This nutrient works as a counter to excess calcium in the cells. When
there is excess, the oxidation process can be fueled. Magnesium will minimize the
oxidative stress on the cells. This stress can be one part of the autoimmune thyroid
issue.
d.
Unrefined Salt – The sodium in the salt binds with the bromide that is released by the
iodine and carries it out of the body through the kidneys. Unrefined salt contains over
80 minerals and is very supportive of the adrenal glands which can be stressed during
the detox process.
e.
Optional– ATP CoFactors (B2/B3) – You will see this recommended as a must have for
all individuals who are supplementing with iodine. This is not the case. I prefer to teach
individuals to start with the basic protocol. This will allow them to know what has
helped them on their journey to better health. Adding too many things at one time
does not allow the person to know if it helped them or not.
What do the ATP CoFactors do? These two nutrients are needed by the cells to
produce more H
2
O
2
to assist in the oxidation process of Iodine. It also stimulates the
NADPH pathway. This is where iodide is converted to iodine. This can be important to
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those who suffer from autoimmune conditions such as Hashimotos where the oxidation
process creates oxidative stress on the cells. (TPO Abs would be an example of oxidative
stress) It can also be considered for conditions like Fibromyalgia where the “energy
factories – ATP” are not functioning at optimum levels. Dr Abraham also determined
that ATP Cofactors could be beneficial in healing the organification process. (Tg Ab may
be an indication of this issue.) This is the binding of iodine to thyroglobulin in the
hormone creation process.
This supplement can be considered at the beginning for those struggling with these
conditions or the individual may wish to wait to see if they make progress with the basic
protocol alone in an effort to keep the cost of supplements down.
5.
When should I take my supplements? Do I need to space them
apart?
a.
Iodine should be taken with food. This seems to enhance absorption as well as
protecting sensitive stomachs from a potential upset especially with the liquid form.
b.
Some have expressed concern with combining Vitamin C and Iodine. This is because
when placed in a container together the color of iodine is removed which signifies a
change in chemistry. However, this has never been tested in the body. The stomach
environment is different than a glass container. If there is concern on your part, then
separate by 30 -60 mins. The tablet / capsule forms of Lugol’s formula should not cause
any concern when combining.
c.
All of the supporting nutrients can be taken with iodine and with food.
d.
Iodine should be taken earlier in the day (before 2 pm) because for some it increases
energy and wakes up the brain so much that they are unable to sleep.
6.
Does iodine destroy good bacteria?
No, you do not need to worry. Iodine functions as an adaptogen – meaning it “knows” what
does not belong and works to destroy the bad bacteria in the gut. It does not destroy the good
bacteria (probiotics). Remember, this is a natural element and not a drug. Anti-bacterial drugs
are broad spectrum in most cases and work by removing all bacteria whether it is good or bad.
This is why natural remedies are often the best option.
7.
How long should I take Iodine?
Dr. Abraham stated that it would take approximately 6 months of 50 mgs of supplementation to
reach 90% saturation. However, as more and more people have done the 24 hour loading test,
this is not what has actually occurred. It seems that this level is taking many years to obtain.
This depends on the exposure to halides
a.
Diet – are you consuming bromides in your food or drinking water with fluoride
b.
New consumer goods recently purchased – items like automobiles, carpets, electronics
and mattresses can be high in bromide which causes exposure.
Supplementing with iodine is a lifetime endeavor. You will not be able to get your
required iodine amounts from food our soil because it is depleted
.
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8.
Where can I buy non-liquid Lugol’s products?
I offer Lugol’s formula supplements on my website and a partner site. Selling iodine and
supporting health products allows me to continue to offer free assistance to the members of my
Iodine groups. Your purchase helps me to continue to do this. Thank you!
a.
www.steppingstonesliving.com/shop/ - This is my website. I offer a variety of iodine
products. Products include: LugoTabs, Iodoral, IodoRX, i-Throid, and Iodine Complex
as well as the supporting nutrients and other health related products. Your purchases
help me to continue to be able to support you on the Yahoo and Facebook groups free
of charge.
b.
http://www.cpmedical.net/steppingstonesliving/ - this is also a site affiliated with my
practice. It offers Iodoral and IodoRX and supporting nutrients. You may also be able
to have these items shipped to you internationally along with other health products.
9.
What is the Salt Loading Protocol?
This is not to be confused with salt supplementing.
Perform the salt loading protocol when you are experiencing detoxification symptoms
with iodine supplementation. This protocol was developed by Dr Shevin and shared at
the 2007 Iodine Conference.
**Note- You should not need to do this for more than 3 days. If your symptoms persist
then you need to consider reducing your dose of iodine.
1/2 tsp celtic (or other unrefined) salt in 1/2 cup of warm water
Follow the above with a glass of 12 oz filtered water.
** Repeat every 30-45 minutes as needed until urination begins.
Why does this help?
Salt - containing chloride - binds to the bromide in the blood stream and carries it out
through the kidneys.
10.
What are the sources of Bromide?
Over and over people come to the Iodine group claiming that they can’t possibly be toxic in
bromide because they are gluten free, eat a clean diet, etc. Guess what? It isn’t diet related in
most cases. Bromide is a flame retardant that is used in and on many items around you. These
include carpeting, furniture, mattresses, clothing, computers, iPhones, and automobiles – just to
name a few. Food sources can include items like baked goods that contain brominated flour or
vegetable oil as well as soft drinks like Mountain Dew and other citrus based sodas. It can also
be found in some Gatorade products. For many years it was used in the form of Methyl
Bromide as a pesticide on strawberries.
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11.
Validity of the Iodine Patch Test
You cannot consider that you are deficient or sufficient based on the patch test on the skin.
There are too many variables that change its absorption. It isn’t very scientific. Read the
following article by Dr. Abraham for more information
http://www.optimox.com/pics/Iodine/updates/UNIOD-02/UNIOD_02.htm
12.
My ferritin dropped while on Iodine.
This has been happening to some people taking 50 mgs or more of Iodoral. It has been rectified
by adding a B6 – Complex along with an iron supplement to help restore ferritin to normal
levels. It is thought to occur due to an increase in metabolic rate that requires more iron.
Sufficient ferritin levels (60-70) are needed to create and utilize thyroid hormones. Please note
that this is not something that happens to everyone so do not worry that it will happen to you.
The information is provided to share what might happen and what to do if it does.
13.
I am gaining weight since starting Iodine.
Unfortunately this can occur in those that are toxic and have sluggish detox pathways. If your
detoxification pathways are not able to eliminate the toxins being released by iodine then your
body will buffer them with water and fat. It may be due, in part, to lowered calcium levels as
well as magnesium, vit D, and B Vitamins. All work to maintain balance in the cells and
eliminate toxins. There are some detox products that can be viewed on my website here:
www.steppingstonesliving.com/shop/ under the category of Detoxification that can support
your body’s ability to detox.
14.
Iodine Supplementing & Mercury Filings
While iodine does seem to pull out some mercury from the cells / tissues of the body, there has
been no indication that it is dangerous to take iodine while amalgams remain in the body. If
there is any concern, supplements like cilantro, chlorella and alpha lipoic acid (ALA) can be used
to help bind and carry the mercury out of the body. Consulting with a good holistic / biological
dentist as well as a holistic medical doctor can help you to assess your toxicity level and assist
you in safe removal of amalgams and chelation.
15.
I have Hashimotos. Can I take Iodine?
Yes, Dr. Brownstein believes that low iodine is one the key causes in autoimmune thyroid
disease. The following is an excerpt from Dr. Brownstein’s Iodine book.
THE UNDERLYING CAUSE OF AUTOIMMUNE THYROID ILLNESSES:
IODINE DEFICIENCY AND ANTIOXIDANT DEFICIENCY
Chapter 7 described the apoptotic (i.e., anticancer) effects of the iodinated form of lactone (δ-
Iodolactone).
δ- Iodolactone is not only important for preventing cancer, its production is also necessary to help
regulate the oxidation of iodine. Figure 3 illustrates this regulatory step in the
oxidation/organification of iodine.
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As previously mentioned, the oxidation of iodide to iodine occurs through the interaction of H
2
O
2
and TPO. Iodine is a necessary product in order to provide the correct molecule in the cell so that
organification can occur. If organification does not take place or is blocked, thyroid hormone and
iodo-lipids will not be formed. As can be seen from Figure 3, this reaction is controlled by
intracellular calcium levels and iodinated lipids—
δ-iodolactone.
Intracellular calcium stimulates this pathway. On the other hand, δ-iodolactone and other iodinated
lipids act as a brake on the system. If there is not enough iodine in the cell to organify and produce
adequate amounts of δ-iodolactone, it can set the stage for damage to the thyroid cell and the
development of an autoimmune thyroid disorder such as Hashimoto’s or Graves’ disease.
A Proposed Mechanism for the Development of
Autoimmune Thyroid Disorders
The NADPH oxydase system is found in the mitochondria of our cells. The mitochondria are the
energy-producing cells of our body. The mitochondria produce energy (i.e., ATP) through a complex
process called oxidative phosphorylation. All medical students (and most physicians) are familiar
with oxidative phosphorylation because we have to memorize the many steps responsible for
producing ATP. This production of ATP requires many items including: oxygen, magnesium, ADP,
and amino acids.
Many people with chronic illnesses, such as fibromyalgia, chronic fatigue syndrome, and autoimmune
disorders, complain they have no energy. ATP is the molecule that stores energy for the body. The
body is constantly producing and utilizing ATP. Its production is a complex process that is beyond
this book. However, there are two cofactors, Vitamins B2 (riboflavin) and B3 (niacin), that are
integral to stimulating oxidative phosphorylation and ATP production.
Hydrogen peroxide is a byproduct of oxidative phosphorylation. It is this production of hydrogen
peroxide that is so critical to the oxidation process of iodine. Hydrogen peroxide and TPO help to
oxidize iodide to form iodine.
If there is a deficiency in iodine, which is common when ingesting the RDA for iodine, there will not
be enough substrate (i.e., iodine) to produce iodinated lipids. As can be seen from Figure 3, the lack
of δ-iodolactone and other iodinated lipids results in a loss of the ‘brake’ in the pathway to oxidize
iodide. This may result in a temporarily production of too much hydrogen peroxide. This excess
hydrogen peroxide can damage the enzyme TPO.
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What Happens If TPO Is Damaged? Autoimmune Thyroid Illness
The body’s response to TPO damage is to produce antibodies against TPO or anti-TPO antibodies. A
diagnosis of Hashimoto’s disease requires the presence of anti-TPO antibodies. As the damage
worsens, surrounding proteins can also be damaged such as thyroglobulin. Damaged thyroglobulin
will result in the body producing antibodies against thyroglobulin—anti-thyroglobulin antibodies.
In most cases of Hashimoto’s disease, there are antibodies to both TPO and thyroglobulin present.
Although Graves’ disease may also possess these same antibodies, antibody production is not
necessary to make the diagnosis of Graves’ disease. However, my clinical experience has shown that
the treatment for both Hashimoto’s and Graves’ disease can follow a similar course with similar
positive outcomes.
How to Treat Autoimmune Thyroid Disorders
1. Ingest enough iodine in order to provide adequate substrate to iodinate lipids.
2. Take Vitamins B2 (Riboflavin) and B3 (Niacin) in amounts necessary to stimulate the NADPH
system to produce adequate amounts of H
2
O
2
.
3. Correct oxidant stress in the thyroid gland and the mitochondria with antioxidants.
4. Ensure adequate magnesium levels.
5. Minimize oxidative stress in the body.
16.
Why does iodine work for Hashimotos?
There are many healthcare professionals that are warning of the terrible consequences for
those with Hashimotos who take high doses of iodine. But they are VERY wrong. The lack of
iodine is actually part of the reason as to why Hashimotos has occurred. Iodine is needed to
support the body in balancing this autoimmune condition. There are several things that you
need to look at and consider when listening to these doctors warnings.
a.
How much iodine do they discuss? In most cases they discuss microgram (mcg) or low
milligram (mg) dosing in the examples they site that had outcomes resulting in disaster.
Yes, this is exactly what may happen. In some individuals when given microgram
amounts you do “stoke the fire” and cause an increase in antibody attack on the thyroid
gland. That’s not what we teach.
b.
Where do they stop their discussion? In watching many videos and reading the articles
of the doctors sounding the alarm, they take iodine through the biological process in the
gland where iodine enters the cell and is oxidated from iodide to iodine and then they
exclaim – “See the oxidation creates inflammation and that increases antibodies.” Right
again! But there is one problem. The body’s process doesn’t stop there. When iodine
is supplied in levels OVER what is needed to create thyroid hormones there is a magical
substance that is created called iodolipids. These iodolipids are the regulatory factor on
the oxidation process. Iodolipids, when created, will put the brakes on the oxidative
process before it runs out of control and “burns” the cells creating an inflammatory
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response. The body sees inflammation / abnormal cells and creates and antibody attack
against them as a natural response. The key is to stop this from occurring.
c.
Where they go wrong. Dr Brownstein has written about this in his book Iodine Why you
Need it Why You Can’t Live Without It. He has determined that when iodine is supplied
in amounts 100x the RDA of 150 mcg (or 15 mgs) that the body will begin to create
these iodolipids. So you can see that giving microgram amounts causes a big issue for
those with Hashimotos. In this case the mantra of “low and slow” can actually create a
bigger issue. This causes many to give up on iodine because their condition seems to
worsen. So the next time you see a doctor or listen to one that discusses the dangers of
high doses of iodine for Hashimotos ask them…. “What about the iodolipids?”
17.
My TSH went up on Iodine.
This is a common occurrence when a person starts to take iodine after being deficient. The
body increases TSH to stimulate production of thyroglobulin which is used to bind to the iodine
in thyroid hormone production. TSH is also the method the body uses to stimulate the NIS
(sodium iodine symporters) to take iodine into the cells. Individuals can have TSH levels as high
as 75 for up to 6 months without clinical signs of hypothyroidism. To monitor your thyroid
“health” accurately, labs that check the Free T3 and Free T4 should be run. You will find in most
cases that the “frees” are nicely within the ranges while the TSH remains high.
18.
I have adrenal fatigue. Can I take Iodine?
Yes, Iodine is used by every gland and mucosal lining and is needed to heal the adrenals. You
should also use unrefined salt to support them as well as Vitamin C. Other products such as
ashwaganda, licorice root, rhodiola, and adrenal glandulars can help to support the adrenals. In
severe conditions a doctor can prescribe hydrocortisone (HC) to replace the body’s deficiency.
19.
I have breast cancer and would like to learn more about using Iodine.
The best resources for learning about breast cancer and iodine is the book by Dr. David Derry. It
is called Breast Cancer and Iodine: How to Prevent and How to Survive Breast Cancer. Dr
Brownstein’s Iodine book also contains valuable information.
20.
Bromide Toxicity and Iodine Loading Test.
As the years go by, members of the group have been testing relatively high in their saturation
levels with the Iodine loading tests. This is usually met with jubilation that they are at a good
level. But wait! This isn’t a place to stop. A bromide level test should be added to the loading
test. It is highly recommended because it gives a clearer picture of what the TRUE status of the
saturation level is. As a general rule if you see a higher saturation level (80% or above) with a
bromide level over 5 mgs/L (the upper limit of normal per Dr. Guy Abraham) you are bromide
toxic and the receptors that would normally be able to pull iodine into the cells cannot because
bromide is blocking the receptors. Because they are blocked, it would result in a high level of
iodine being eliminated in the urine indicating (falsely) that you are more saturated than you
are. Persons with results such as these should consider supplementing with Lugol’s formula
(liquid or tablet) in doses of 50 mgs or more for 6 mos to 1 year and then retest with the 24 hour
Iodine Loading and Bromide level test to see what the new levels are.
Another reason for a false high reading in saturation levels is due to defects in the symporters of
the cells. Symporters are the “pumps” that pull iodine into the cells. Dr. Abraham addresses
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this on his website at http://www.optimox.com/pics/Iodine/IOD-11/IOD_11.htm which suggests
the usage of Vitamin C to heal symporters.
21.
Ordering a 24 hour Iodine Loading Test with Bromide Levels.
It is recommended that you order both the 24 hour loading and bromide level test. We
recommend this because you may obtain a high saturation level and believe that your levels are
fine when in fact bromide toxicity will block the iodine receptors not allowing iodine to enter the
cell which results in an elimination of iodine when it is needed / deficient thus skewing the test
results.
The following list is a compilation of resources for obtaining the Iodine loading test.
Hakala Research
885 Parfet Street Unit E
Lakewood, CO 80215
877.238.1779
*** It is not recommended that you do the spot test as this is only an indicator of how much
iodine is in the diet and the amount that has been ingested in the last 24 – 48 hours. It offers
no real value to determining the body saturation level. The two asterisk items are the
recommended tests.
** Iodine Loading Kit Only $70
Iodine Spot Level Kit Only $70
Iodine Spot and Loading Kit $95
** Bromide Level Testing (must be combined with one of the above kits) $35
Test prices do not include return shipping.
They now also offer iodine serum/saliva testing to check for Organification / Oxidation issues
as well as symporter defects. The test is available two ways:
1. 24 hour Iodine loading test plus the serum saliva ratio cost: $155.00.
2. Serum saliva ratio without the urine test cost: $110.00.
The serum/saliva ratio gives the degree of usage of iodine within the cell, if the ratio is
below normal this signifies a symporter defect (NIS) while a higher than normal ratio
points to an organification problem.
According to Dr. Abrahams articles the symporter can be repaired using 3 gm of slow
release Vitamin C per day, the organification issue responds to ATP CoFactors
(Riboflavin 100mg + NoFlush Niacin 500mg) twice daily.
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=============================================================================
FFP Labs
Dr. Jorg Flechas MD
80 Doctors Drive Ste 3
Hendersonville, NC 28792
(1-877-900-5556)
The cost of this test is $80.
If it is not ordered by a physician you must tell them you are ordering it on your own
and they will assign you to a nurse practitioner. When you get the results of this test
you can receive a free consultation with Dr. Flechas.
You may also obtain a urine spot test for an additional $30 for a total of $110 for both tests.
Spot / Loading / Bromide test can be obtained for $230
=============================================================================
Doctors Data
** This lab does not seem to report in the manner that is described in Dr. Abraham’s research
so it is difficult to determine true saturation and bromide levels.
Pre and post loading - requires an ordering physician.
====================================================================================
ZRT Laboratories (No on this one)
This test is not performed in the manner outlined by Dr. Abraham, Dr Brownstein or Dr. Flechas
and which has been used effectively since the 1990s. It has not been proven to correlate with the
health conditions of those with iodine deficiency and does not offer a bromide level test which is
critical in determining how accurate the saturation level is. At this point the Iodine group does
not recommend this test.
22.
Recommended Reading.
Many of the questions asked over and over are covered in these reference materials. Please
familiarize yourself with them to help with limiting the repetition of information on the group.
The Brownstein books can be purchased on my website at
www.steppingstonesliving.com/shop/
a.
Dr David Brownstein – Iodine Why You Need It, Why You Can’t Live Without it
b.
Dr. David Brownstein – Salt Your Way To Health
c.
Dr. David Derry – Breast Cancer and Iodine: How to Prevent and How to Survive Breast
Cancer http://www.thyroidscience.com/reviews/derry/derry.9.19.09.htm
d.
www.optimox.com - Research by Dr. Guy Abraham – the founder of The Iodine Project
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23.
Detoxification
Your body’s ability to detoxify chemicals and other toxins from the body is one of the most
critical functions in obtaining optimum health. Without the elimination of toxins the entire body
will struggle to operate. When your body is bogged down it will work hard to protect you at all
costs from these toxins while compromising other functions such as hormone balance, blood
sugar control, skin tone and mental clarity, energy and even things like fertility.
Supporting the Detox Pathways
How does the body detox?
1.
Skin
2.
Lymphatic System
3.
Liver
4.
Kidney
5.
Intestinal System
The liver performs a 2 phase detoxification process:
Phase 1 – This phase consists of oxidation reduction and hydrolysis. Simply put it takes a toxic
chemical and turns it into a non-toxic one.
Phase 2 – This pathway is called the conjugation pathway where the liver cells add another
substance (like cysteine, glycine or a sulphur molecule) to a chemical that is toxic to the body
that renders it less harmful. This makes the toxin water soluble so that it can be excreted easily
from the body through the water containing fluids like bile or urine.
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The following chart outlines the nutrients required by each phase to function at optimum levels
as well as some supporting nutrients to assist the process.
Phase 1
Phase 2
Vitamin B2, B3, B6 and B12
Vitamin B5, B12
Folic Acid (L-5- Methyltetrahyrofolate
better form – especially for MTHFR
defect)
Folic Acid (L-5- Methyltetrahyrofolate
better form – especially for MTHFR
defect)
Glutathione
Magnesium
Citrus Bioflavonoids
Gluthathione
Vitamin A
Methionine
Vitamin C
Vitamin C
Calcium
Choline
Vitamin D3
Taurine
Vitamin E
Cysteine
Milk Thistle
Calcium d-glucorate
N-acetyl Cysteine
Amino Acids:
Quercetin
L-Carnitine
L-Glutamine
L-Lysine
Glycine
Taurine
Cruciferous vegetables (sulfur
metabolites)
MSM
N-acetyl Cysteine
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Liver Detoxification Process
Toxins (Fat Soluble)
Phase 1 Detox Pathway
Phase 2 Detox Pathway
Waste Products Eliminated from the body via:
(Water Soluble)
Gall Bladder
Kidneys
Bile
Urine
Intestines
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Digestive Toxin Elimination
The Digestive system is equipped to detox fat soluble toxins from the body if functioning properly.
During the fat digestive process, bile is released from the liver. This bile can also contain the conjugated
toxins from the Phase 2 liver process.
In order for the liver to function properly and produce enough bile, adequate protein is essential. Amino
acids are critical for phase I and 2 liver detoxification. L-Taurine is essential for bile formation. Cysteine
is the precursor to the antioxidant Glutathione. Glutathione cleans up free radicals and toxins that end
up in the bile that is excreted to the intestines. Hydration is critical during this process because 85% of
the bile is made of water. The nutrient Betaine (trimethylglycine) is a powerful liver detoxifier. Betain
can be found in the highest concentrations in beets and beet greens.
The bile that is excreted during digestion breaks up the fat into tiny pieces. These pieces then enter the
intestinal tract where villi on the wall of the intestines (sweeping back and forth) pick up the particles
with the toxins and pull them off the wall and through the intestinal lining into the gut associated
lymphatic tissue. These villi also pull off good fats as well (nutrients). If the bile is not adequate from
the liver then these fat soluble toxins will not be broken down adequately.
Gut associated lymphatic tissue on the outside of the intestinal tract is approximately ¼ inch in size. Fat
soluble chemicals are pulled through the villi into this tissue and attacked by the white blood cells of the
lymphatic system where they are processed by over 500 lymph nodes and neutralized for the body to
detoxify and carry them out.
If you have a sluggish lymphatic system or congestion issues it will be presented in things like allergies,
belly fat, itchiness, fatigue, headaches, cellulite, and breast swelling and tenderness.
The integrity of the villi is important. If you have chronic stress, constipation, or irritation of the bowel a
reactive mucous may form which cause the villi to stick to the wall of the intestines thus inhibiting it
from absorbing not only the toxins but also the fat soluble nutrition.
When the malabsorption occurs, then toxins will move on to the large intestines. The bile will hook up
to the chemicals and pull them back into the liver. 90% of the bile gets reabsorbed into the liver. The
liver becomes overwhelmed and congested. The bile then becomes thick and doesn’t flow as well.
Which means that you won’t have enough bile to detoxify the fats that come through the next time.
If the liver becomes too congested, it will send the fats back out into the blood stream. The blood
stream will look for fatty tissues to store them in and they will go into the fat cells. (Pathway: Liver to
Blood to Fat Cells) The most common fat cells that they find are in our brain. As we age and become
more toxic we lose memory, cognitive function and clarity. This is due to toxic fat soluble build up in the
brain.
The key to detoxification is to optimize digestion.
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Fat soluble toxins – heavy metals, parasites, pesticides, bad bacteria and other cancer causing
chemicals.
Indicators of an issue –
1.
Blood sugar imbalance
2.
GERD / acid reflux
3.
Allergies
4.
Skin issues
5.
Hormone imbalance
6.
Mucous in stools
7.
Constipation
8.
Loose stools
9.
Belly fat storage
10. Feeling nauseated after a meal (especially high in fat)
FIBER - Another issue with “re-poisoning” of the body is low fiber diets. If we don’t eat enough soluble
fiber, our bile is repeatedly circulated instead of being ushered out of the body (toxins and all). Over
time it becomes very concentrated with toxins which can lead to inflammation, gall bladder disease,
intestinal inflammation, skin issues – like acne, eczema and psoriasis. Remember that the inflammation
of the intestines creases the mucosa that causes the villi to get stuck to the wall and not absorb the fats
into the outer layer for detoxification. This also makes you nutrient deficient due to malabsorption.
Cellular toxicity
The cellular wall is made of lipids and proteins. Because of this lipid soluble compounds are able to pass
freely into it gaining free access to the cellular interior. This is where it becomes much more difficult to
remove the toxins. It is best to keep the toxins moving out (as described above) than to allow them to
be stored because of a congested detoxification system.
Blood acidity is one of the biggest hindrances to detoxifying the cells. Acidity can come from the foods
we eat, beverages we drink as well as low levels of oxygen content. We need to keep our body in an
alkaline state to assist with detoxification.
Some strategies to alkalize the body:
1.
Start your morning with clean filtered water with lemon juice. Drink ½ your weight in ounces
throughout the day (150 lb person would drink 75 oz)
2.
Eat foods rich in alkalizing minerals
3.
Consume unrefined salt rich in minerals
4.
Snack on raw almonds. These are rich in magnesium and calcium which helps to maintain
alkalinity in the body.
5.
Eat less red meat. This can have an acidic effect on the body
6.
Increase the number of vegetables in your diet.
7.
Take deep breaths. Many people take shallow breaths. Concentrate on filling your lungs with
oxygen several times to increase oxygen in the blood stream.
8.
Exercise – This is one of the best ways to increase oxygen, get the lymphatic system moving and
increase toxin elimination.
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24.
Importance of Healthy Gut Flora
Another culprit in the detoxification arena is the importance of healthy gut flora. The
gastrointestinal tract is approximately 25 feet long. Within this intestinal tract are friendly
bacteria and not so friendly bacteria. When the unfriendly bacteria become the dominant force,
trouble occurs. This is called gut dysbiosis.
The gut has three primary functions:
Digestion of foods & converstion to vitamins
Absorption of nutrients
Prevention of pathogens and toxins from entering the body
There are approximately 500 species of bacteria along with yeast and other organisms in the
gastrointestinal tract. These items are what make up the gut flora. The friendly bacteria are
vital for proper digestion and for maintaining the overall health of the intestines. Most of these
bacterial have names that begin with “Lactobacillus” or “Bifidobacteria”. These are the classes
of bacteria that they belong to.
Disruption of the balance of the organisms in the intestinal tract can lead to an overgrowth of
the bad forms of bacteria. Several factors can be indicated in this degradation.
Use of hormones such as immunosuppresssants (like steroids)
Alcohol
Stress
Antibiotic usage (abuse of)
Diet high in sugar and refined carbohydrates.
The dysbiosis of the gut can often be seen in medical conditions such as acne, food allergies,
depression, and chronic fatigue. A beneficial balance of the good bacteria can be restored
through supplementation of prebiotics and probiotics. If left untreated, the dysbiosis will result
in leaky gut syndrome which causes the lining of the bowel to increase permeability of the
intestines allowing toxins to pass through to the blood stream.
Healthy gut bacteria has an important role. It is responsible for synthesizing all the B Vitamins
along with Vitamin K and amino acids. These bacteria also “grab” toxic chemicals, heavy metals,
and carcinogenic environmental toxins. It either holds on to the toxins and is eliminated
through the colon or neutralizes it. It stops the toxins from passing back into the blood stream.
25.
Detox Strategies
Saunas - Infrared Saunas can be a beneficial tool to the detoxification process. Since the skin is
the largest detoxification organ it is a great way to remove them. This also improves circulation,
increases oxygenation and helps to eliminate congestion.
Dry Brushing – This can help to boost circulation and stimulate the lymphatic system to release
toxins. It also helps to remove dead skin that can clog pores where toxins can be released.
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Using a natural brush, gently brush in a circular movement towards the heart. Start at the soles
of your feet working up your legs and then move to your hands and arms. Brush your back from
your buttocks up and around to the stomach. Brush the stomach area with a counter clockwise
motion.
Detox Baths – Detox baths can be beneficial especially when dealing with skin breakouts. Add
the following items to very warm water and soak for 20 mins. Double the recipe for a large tub.
These baths can be taken several times a week.
1 Cup Epsom Salts or Dead Sea Salt
1 Cup Hydrogen Peroxide
½ Cup Baking Soda
28 Day Food Elimination and Detoxification – Metagenics offers a 28 day detox program that I
used when fighting cancer. I completed one 28 day cycle before my last round of radioactive
iodine and then again after I received my last treatment. It is not an easy task to perform but I
will testify that it is worth it. I felt better than I had in years. My joint pain was relieved, brain
fog lifted and I even lost weight. This protocol involves the usage of 3 canisters of the product
and a strict dietary program. During this time you will eliminate foods that can be inflammatory
or an allergen for many and then they are slowly added back after the program is complete.
This allows you to adequately evaluate what may be causing issues with your body.
Milk Thistle – Studies have shown that milk thistle can help to protect and promote the growth
of liver cells. It helps to fight oxidation which protects the cells from damage. In 16 trials by the
NIH they also concluded that the supplement helped to protect the liver through antioxidant
activity, enhanced protein synthesis, and toxic blockade at the membrane level that inhibits
membrane peroxidation. Milk thistle helps to slow the depletion of glutathione which is
important for the phase 2 detoxification process in the liver.
Dandelion Root Extract – The root of this plant can act as a mild laxative. It has also been
known to improve digestion. Preliminary research suggest that dandelion may help to improve
the function of the liver and gallbladder. In folk medicine it is used as a liver stimulant and tonic.
The University of Maryland Medical Center has indicated that dandelion root may boost the
production of beneficial bacteria in the intestines.
Yellow Dock – In traditional medicine yellow dock has been thought to be a blood purifier and
detoxifier of the liver. Yellow dock stimulates bile production which aids in digestion. It is
effective in preventing toxins from entering the gallbladder, bloodstream and liver.
Lymphomyosot – This is a homeopathic formula from HEEL that is used to support the
lymphatic, immune and circulatory systems. The formula contains homeopathically prepared
herbs that are intended to promote lymphatic health by reducing swelling from poor circulation
and environmental toxins. Assists in normal detoxification. May support lymphatic function.
May support circulation.
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26.
Final thoughts as it relates to Iodine Supplementing Detox…..
One of the blessings and a curse of iodine supplementing is that toxins are released in the body.
It is a blessing because bromide, fluoride, mercury and lead are released from the cells so that
the healing can begin. But the curse comes from the large amount of toxins being released
which in most cases, cannot be eliminated quickly and effectively. The average person has no
idea just how toxic they become. By the time illness sets in, the toxicity is more than likely very
high. There are some who begin iodine supplementing and feel no detoxing effects while others
have terrible side effects that are triggered by just a small amount of supplementing. Still more
experience weight gain. I believe that the information in this document holds the key to this
issue and offers options for dealing with it.
If you are going to embark on an iodine supplementing protocol it would be a prudent to assess
your current toxicity status. Do you have any of the symptoms that were listed previously that
may indicate a congested detoxification system? If yes, then it may be best to undergo a detox
program prior to beginning iodine. A few weeks of concentrated support with the purpose of
increasing bile, cleaning up the diet and cleansing the body will offer a better start to your
journey.
If you are experiencing detoxing while supplementing, the strategies listed previously can help
to lessen the severity of the process. Intermittent supplementing (taking iodine a few days on
with a few days off) is a strategy that I used when toxic and detoxing faster than my body could
handle. During this time you continue to take the supporting nutrients outlined in the Guide to
Supplementing while taking a break from iodine. The Salt Loading protocol can also help to
move bromide out of the body more quickly and effectively so that it is not recirculated and
stored in the body.
The saying “No pain no gain” is not something you want to strive for. The goal is to
supplementing with enough iodine to release toxins while not releasing too quickly so that it
stresses the body and overloads the detox pathways. A steady low level detox that is well
supported will get you to your destination – abundant health.
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27.
INDEX
Adrenal fatigue................................................. 11
Antibodies ........................................................ 10
Atomidine iodine................ See Detoxified iodine
ATP ................................................................. 6, 9
ATP CoFactors
as optional supporting nutrient .................... 4
physiology ...................................................... 9
Autoimmune thyroid diseases
mechanism causing ........................................ 9
treatment of ................................................. 10
underlying cause ............................................ 8
Breast cancer ................................................... 11
Bromide testing
in combination with iodine loading test ...... 11
ordering .................................................. 12, 13
second testing .............................................. 11
Bromides ......................... See also Detoxification
and the iodine loading test .......................... 11
bombarding our systems ............................... 4
normal levels of ............................................ 11
sources of ....................................................... 7
Calcium, weight gain and ................................... 8
Cancer
breast cancer................................................ 11
how much iodine to take ............................... 4
Celtic sea salt......................... See Salt, unrefined
Chelation, mercury amalgam fillings and .......... 8
Children Supporting Nutrients ........................... 4
Children, how much iodine to take .................... 4
Chlorine, as halide, bombarding our systems .... 4
Companion nutrients ... See Supporting nutrients
required
Dental mercury amalgam fillings ....................... 8
Detoxification
forms of iodine not producing ....................... 3
symptoms of, salt loading protocol to
alleviate ...................................................... 7
Detoxified iodine
amount of iodine in ........................................ 3
for children under 3 years .............................. 4
Digestive tract health ......................................... 6
Doctors Data (laboratory) ................................ 13
Ferritin levels dropping ...................................... 8
FFP Labs ............................................................ 13
Flame retardants, as source of bromides .......... 7
Fluoride, as halide, bombarding our systems .... 4
Food
as source of bromides.................................... 7
probiotics and iodine ..................................... 6
taking supplements with ............................... 6
Forms of iodine .................................................. 3
Free T3, and rise in TSH ................................... 11
Free T4, and rise in TSH ................................... 11
Good bacteria, and iodine ................................. 6
Graves' disease
antibodies and ............................................. 10
treatment of ................................................ 10
underlying cause of........................................ 9
Gut health and iodine ........................................ 6
Hakala Research (laboratory) .......................... 12
Halides ........... See also Bromides; Detoxification
list of types of ................................................ 4
Hashimoto's disease .......................................... 8
cause underlying ............................................ 8
mechanism causing ....................................... 9
treatment of ................................................ 10
How much iodine to take
cancer ............................................................ 4
children .......................................................... 4
maintenance .................................................. 3
with false saturation results ........................ 11
Iodinated lipids .................................................. 9
Iodine
dosage ...............
See How much iodine to take
forms of ......................................................... 3
saturation with ......
See Saturation with iodine
testing .......................
See Iodine Loading Test
when to take .................................................. 6
Iodine Loading Test
and bromides, effect on results of .............. 11
ordered with Bromide Levels Test ............... 12
ordering ....................................................... 12
second testing, time for ............................... 11
Iodine Spot Test ............................................... 12
Iodoral
how much to take .......................................... 3
where to buy .................................................. 7
Lugol's liquid iodine
how much to take .......................................... 3
Magnascent iodine ............ See Detoxified iodine
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Magnesium
as supporting nutrient, amount to take ........ 4
weight gain and .............................................. 8
Mercury
amalgam fillings in teeth ................................ 8
bombarding our systems ............................... 4
Nascent iodine .................. See Detoxified iodine
Niacin
as optional ...................................................... 6
in treatment of autoimmune thyroid diseases
................................................................. 10
no-flush, amount to take ............................. 12
physiology and ............................................... 9
Oxidation/organification of iodine
ATP CoFactors to treat ................................. 12
physiology ...................................................... 8
test to check function of .............................. 12
Phosphorylation ................................................. 9
Pregnancy / Lactation ........................................ 3
Probiotics and iodine ......................................... 6
Resources
cancer and iodine ........................................... 4
Dr. David Brownstein books ......................... 13
Dr. David Derry article .................................. 13
Dr. Guy Abraham articles (Optimox site) ..... 13
skin patch test ................................................ 8
where to buy Iodoral ..................................... 7
Riboflavin
amount to take ............................................ 12
as optional ...................................................... 6
in treatment of autoimmune thyroid diseases
................................................................. 10
physiology and ............................................... 9
Salt loading protocol .......................................... 7
Salt, unrefined
adrenal fatigue and ...................................... 11
as supporting nutrient, amount to take ........ 4
function in body ......................................... 4, 7
in salt loading protocol .................................. 7
Saturation with iodine
and false readings ........................................ 11
Detoxified iodine not providing ..................... 3
Selenium
and cancer ..................................................... 4
as supporting nutrient ................................... 4
Supporting nutrients required
amounts and functions .................................. 4
when to take .................................................. 6
Symporter defects
and false high reading in saturation levels .. 11
test for ......................................................... 12
Vitamin C in treatment of ............................ 12
T3, free .............................................. See Free T4
T4, free .............................................. See Free T4
Thyroglobulin ............................................. 10, 11
Thyroid hormones
ferritin in production of ................................. 8
iodine in production of ............................ 9, 11
selenium in production of ............................. 4
TSH rising and .............................................. 11
Time
for second round of testing ......................... 11
of day, to take supplements .......................... 6
TPO .................................................................... 9
TSH rise, following iodine supplementation .... 11
Vitamin B group, and weight gain ..................... 8
Vitamin B2 .................................... See Riboflavin
Vitamin B3 ..........................................
See Niacin
Vitamin C
adrenal fatigue and ...................................... 11
as supporting nutrient ................................... 4
symporter defects healing with ................... 12
Vitamin D ........................................................... 8
Weight gain ........................................................ 8
ZRT Laboratories .............................................. 13
